A group of Russian scientists are working with chemical compounds to stop the degeneration of Alzheimer’s and Parkinson’s Disease. It could become a major breakthrough for the debilitating diseases.
Now Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer’s, Parkinson’s, and other severe brain pathologies.
New molecules of pyrrolyl- and indolylazine classes activate intracellular mechanisms to combat one of the main causes of “aged” brain diseases—an excess of so-called amyloid structures that accumulate in the human brain with age.
“Our compounds activate the synthesis of specific heat shock proteins and cause their accumulation in the cell,” said research co-author, professor of the Department of Organic and Biomolecular Chemistry at UrFU Irina Utepova.
“Proteins of this type make it possible to protect neuronal tissue from an excess of toxic amyloids and to protect cells from various types of stress, including proteotoxic stress characteristic of neurodegenerative diseases.”
Lord knows I’m having trouble remembering things, and when my mother started having trouble I realized this may be a family trait. Hopefully this can lead to a cure.
To Infinity And Beyond Caption Contest
Caption this photo in the comments section. The winners will be posted on Monday, July 26th.
Original Caption: Billionaire businessman Jeff Bezos is launched with three crew members aboard a New Shepard rocket on the world’s first unpiloted suborbital flight from Blue Origin’s Launch Site 1 near Van Horn, Texas. REUTERS/Joe Skipper
Well, the Olympics are here again, so I might as well continue a time-honored tradition here since 2006. Namely, Your Olympic Babe O’ The Day.
Throughout the Tokyo Olympic Games, I will highlight an Olympic babe each day from a different country and a different Olympic sport. Since my ancestors came from Slovakia, our opening ceremonies will focus upon Skeet Shooter, and fabulous babe Danka Bartekova.
Danka is a 36-year old skeet shooter who won the bronze medal in the 2012 London Olympics, and has won fourteen gold medals in the Slovak Championship sine 1999. Suffice to say, she has a lot of talent.
Feel free to click the pics to embiggen.
There are more photos below the fold…
Continue reading “Your Olympic Babe O’ The Day”
So yesterday a gaggle of bosses were congregating around my desk talking about the state of the department. I almost always ignore those conversations, because 1. it’s boring, and 2. there’s nothing we can do to fix this police force.
The conversation continues, and one of the bosses claims the city’s manpower is much worse than we were told. The department always claims we have a 6,000 member police department. No one believes that statistic, because it’s 100% false. Between officers who are injured on duty, posted to irrelevant “teat jobs,” and those under investigation, we’re actually looking at 5,000. At least that’s what I thought…
Continue reading “True Detective Stories”
After a Chinese cyberattack affected at least one million American Microsoft users, the illegitimate president decided to let by-gones be by-gones. Sorry about your personal information, America, but hey, what are ya gonna do?
The Biden administration blamed China on Monday for a cyberattack that compromised more than a million Microsoft customers, but stopped short of sanctioning Beijing for contracting with hackers.
The United Kingdom, European Union, and NATO joined the United States in condemning China for facilitating the March attack on Microsoft Exchange email servers. But President Joe Biden and State Department spokesman Ned Price dismissed the need for retaliation, causing some lawmakers to question the Biden administration’s ability to combat hostile foreign actors.
Now that doesn’t seem right, especially since the illegitimate president is a straight shooter whose first and only concern is the well-being of the American people.
The Biden administration has come under fire for its inconsistent response to foreign cyberattacks. The White House sanctioned Russia in April following Kremlin-directed hacks on critical U.S. infrastructure. But Biden came under fire in June for giving Russian president Vladimir Putin a list of targets that should remain “off-limits” to cyberattacks.
Look, sure the illegitimate president is bought and paid for by the ChiComs, but hey, at least we don’t have to suffer through mean tweets.
Meet Heather A. Kennedy of Charlotte County, Florida. Heather doesn’t appreciate the climate of her home state, so occasionally she decides to swim in other people’s pools. Oh, did I mention she does so without clothes?
A Florida woman is accused of skinny-dipping in a stranger’s pool and refused multiple requests to leave, according to the Charlotte County Sheriff’s Office.
Heather A. Kennedy, 42, is facing charges of trespass in structure or conveyance and resisting an officer without violence. The homeowner told deputies he returned home and noticed a naked stranger in his pool after spotting clothing scattered across the lanai.
Deputies said when they arrived at the Cambridge Drive home Kennedy was hostile toward officers and told them to leave her alone.
In my twenty-six years in police work, I can honestly say Heather would have been the most attractive naked woman I have ever seen if she lived in Philadelphia. Think about that.
Meet William Hodge of Daytona Beach, Flori-Duh. William is an avid fisherman and really likes the excitement of the hunt. Unless, of course, he catches an alligator; then it’s on like Donkey Kong.
According to police, William Hodge, a 32-year-old fisherman, was arrested early today after officers spotted him trying to fling the purloined alligator atop a building in Daytona Beach Shores.
I’ve mentioned this previously, but it bears repeating. NASCAR’s Daytona International Speedway is an amazing place; the rest of Daytona is mostly white trash.
When Hodge’s attempt to launch the alligator failed, Hodge slammed the reptile to the ground and stomped on it, according to a charging affidavit.
When cops approached Hodge, seen at right, he “raised his hands up as if he were giving up and was taken into custody.” Asked what he was doing when throwing the alligator in the air, Hodge reportedly replied that he was “teaching it a lesson.”
The lesson the gator learned is to immediately eat white trash fisherman when you get the chance.
A Massachusetts teenager crashed into the ancestral home of Abraham Lincoln after she swerved to avoid hitting a squirrel. I told you New Englanders drive like maniacs.
A historic house built in 1650 by the great-grandfather of President Abraham Lincoln has been wrecked by a teenage driver crashing into it to avoid a squirrel.
The Samuel Lincoln House on North Street in the town of Hingham, Massachusetts, was badly damaged when a 19-year-old motorist crashed into the front of the historic home on the morning of July 15.
First responders at the scene found a 2014 Audi Q7 lodged in the home’s living room. About half of the car entered the home, according to a statement from the Hingham Police Department.
Right about now, the ghost of Abraham Lincoln is thinking, “Give me six hours to chop down [this chick] and I will spend the first four sharpening the axe.”
Today will be a very big day for Kevin.
A few months ago, I mentioned Kevin took an entrance exam for a really good prep high school back in March. Unsurprisingly, the boy did exceedingly well for a seventh grader. Today, he is scheduled for a thirty-minute interview with the school; twenty minutes alone, and ten minutes with Mrs. Earp.
Kevin jokes about the interview, but it doesn’t seem like he’s stressing over it. I assume he’ll head to the interview, talk to the interviewer, and simply be himself. I have already told him to just go to the interview, and if they want you, cool, and if not, that’s cool, too.
The boy has already suggested the school is entirely too much money – what thirteen year-old does that? – and maybe he should go somewhere else. I told him what I told Kyle when he went to the University of Dallas: “We’ll make it work.”
So, hopefully, Kevin will have a nice, stress-free interview, and I’ll remind Mrs. Earp to tell the interviewer I coached lacrosse at the school for four years. Can’t hurt to grease the wheels, right?
The South Korean president will not be attending the Tokyo Olympics after a Japanese diplomat mad a joke about masturbation concerning the president.
South Korean President Moon Jae-in has decided to shun the Tokyo Olympics after a senior diplomat at Japan’s embassy in Seoul described the president’s faltering attempts to improve the relationship between the two countries as “masturbating.” The Tokyo visit would have seen Moon’s first summit with Prime Minister Yoshihide Suga, and there had been hopes that it could be a fresh start for the two rival nations.
However, the lewd comment infuriated the South Korean government, with its vice foreign minister, Choi Jong-kun, summoning Japan Ambassador Koichi Aiboshi to make a formal complaint over the weekend. “President Moon has decided not to visit Japan,” Moon’s press secretary Park Soo-hyun told a briefing, without specifically mentioning the “masturbation” comment.
I think this is a bit of a nothingburger, but I can also understand boycotting the Olympics. The president was just humiliated, and I’m sure the Japanese fans would love to pile on if he actually showed.